The most common causes are an endocrine disease (hyperthyroidism, pituitary - cushing, thyroidectomy, premenstrual and menopausal syndromes), hormonal drugs in patients with asthma, rheumatoid arthritis, poisoning and overdose of vitamins and antihypertensive drugs, head injuries, tumors of the frontal lobes.
Mood disorders are mixed or manifested in the form of depression, mania, bipolar disorder. Organic background of cognitive deficits can be identified indirectly through a combination of these diseases with a decrease in the activity on the reduction of the energy potential, asthenia, changes in demand (endocrine Psihosindrom), as well the symptoms. Episodes of organic delirium, see history. Manic episodes occur with euphoria and unproductive euphoria (Moria) in the structure of the depression is characterized by dysphoria, mood swings. Evening be exhausted by the mania can be, and depression in the evening increased fatigue. In bipolar disorder in the course of basic pathology is associated, and the seasonality is not typical.
Clinical example: patients L., 52 years old. After Thyroidectomy and against the background of the menopause has become, sad and withdrawn. Your quickly tired at work in the evening, fully curved their appetite, awake at night and could no longer sleep. She noticed that she burden to her relatives, placed as in the House she no longer did they something always in bed. Already in the morning, it was hard to get up. In connection with their own uselessness and cumbersome appeared suicidal thoughts. She noticed that not only was she very thin, but older. She complained to the leader of a small firm of feeling in the chest compression and lack of air in the Einatmen. It is based on the determination of the underlying disease and atypia of mood disorders. Generally may be affective disorders manic depressive, bipolar or mixed.
Disorder should be distinguished from mood disorders on remaining substance dependence, with endogenous affective disorders, symptoms of the frontal atrophy.
Mood disorders due to the remaining drug use can by history, the frequent presence of the typical psychosis (delirium, mood disorders within the abstinence) in history, a combination of mood disorders in a pseudo paralysis or Korsakoff violations are identified.
Endogenous affective disorders are characterized by typical daily and seasonal changes, lack of organic neurological symptoms, it can however secondary endocrine (delayed menstruation, involution).
The frontal atrophy symptoms are characterised by a combination of mood disorders with symptoms of E. Robertson.
In the treatment of organic affective disorders who should therapy should be aware that patients may be unusually responsive, psychotropic drugs, be careful. In the treatment of depression, prozac, zoloft, and Lerivon, preferably should be for the prevention of bipolar disorder - phenytoin, carbamazepine, and sepakin, for the treatment of manic states - carbamazepine, beta-blockers, sedatives and a small dose of Tizertsina. Everything that the so-called therapy is considered to be symptomatic, should take care, the treatment of the underlying disease.